Stay at a luxurious Midtown Manhattan address directly on Lexington Avenue at 48th Street in the heart of New York City's dynamic Midtown East neighborhood. The hotel is located on Lexington avenue on Manhattan's fashionable Eastside. Near Rockefeller Center, the United Nations, Radio City Music Hall, Madison Avenue, Fifth Avenue and the Theatre District.In the heart of the world's most exciting city, find something entirely new at the Lexington New York City, midtown Manhattan's newest Autograph Collection hotel. Awake refreshed from a stay in one of our 725 spacious, newly renovated accommodations, including 38 suites - each designed with you in mind.Take a culinary tour of the world without ever leaving our front door. The Lexington New York City offers guests easy access to some of midtown Manhattan's most popular restaurants , all onsite.deluxe amenities and personalized attention expected from a world-class hotel.